China declared officially outbreak as an epidemic on January 20 after findings of human-to-human transmission. On March 11, 2020, World Health Organization (WHO) declared COVID-19 a global Pandemic after the spread and severity of the outbreak. The virus is transmitted from the infected person through respiratory droplets and by touching the surfaces, contaminated with viruses. At present, India is in the middle of the second wave due to a variant virus. Covid-19 cases have risen faster in the second wave than the first wave in India. Union Health Ministry of India issued the latest guidelines for the treatment of Covid-19 depends upon the severity of the disease i.e. mild, moderate and severe. Ministry of Ayush, Government of India has given guidelines for the treatment of Covid-19. Vaccines are a critical tool in the battle against the COVID-19 war. Covishield and Covaxin vaccines are being administered in India. Even if we are vaccinated, we have to take certain preventive measures until the COVID-19 cases dropdown.