Conclusion

Early-life exposure to dust mite allergen was associated with the onset of wheezing during the age of 0-12 months old and asthma during the age of 12-36 months old. Early-life exposure to endotoxin was also associated with the onset of wheezing and asthma during the age of 24-36 months old. Our results indicated that high levels of early life exposure to dust mite allergen and endotoxin may be involved in the development of asthma.