Study population
The prospective cohort was recruited in FUXING Hospital affiliated to
Capital Medical University in Beijing, China from November 2018 to
January 2020. Inclusion criteria were: 1) naturally conceived; 2)
singleton pregnancy. Exclusion criteria were: 1) women with diabetes
before pregnancy; 2) women with autoimmune disease; 3) women who take
drugs that affect lipid metabolism. Finally, a total of 908 participants
were enrolled in this study. They were followed from recruitment to 42
days postpartum. This study was approved by the Ethics Committee of
Capital Medical University (2012SY29) and abide by the Declaration of
Helsinki principles, and all participants have signed the informed
consent after being fully informed at the first visit. This work was
supported by the National Natural Science Foundation of China [No.
81872608 and No.8207121162].