Statistical analysis
Categorical variables were expressed in proportions, and when there was continuity, they were expressed as mean ± standard deviation (SD) or median and interquartile range (IQR) according to the distribution. Comparisons were made using the Chi-square test or Fisher’s exact test for categorical variables. For dimensional variables, Student’s t or Mann-Whitney U tests were applied. Survival analysis was performed using Kaplan-Meier curves. Kruskal-Wallis test and a post hoc analysis using Dunn’s test. Multiple comparison tests were done with adjustment by Bonferroni correction. Differences were considered statistically significant when the p-value was <0.05. Statistical analyses were performed using STATA version 16 software (College Station, TX).