Statistical analysis
Categorical variables were expressed in proportions, and when there was
continuity, they were expressed as mean ± standard deviation (SD) or
median and interquartile range (IQR) according to the distribution.
Comparisons were made using the Chi-square test or Fisher’s exact test
for categorical variables. For dimensional variables, Student’s t or
Mann-Whitney U tests were applied. Survival analysis was performed using
Kaplan-Meier curves. Kruskal-Wallis test and a post hoc analysis using
Dunn’s test. Multiple comparison tests were done with adjustment by
Bonferroni correction. Differences were considered statistically
significant when the p-value was <0.05. Statistical analyses
were performed using STATA version 16 software (College Station, TX).