Study subjects
This cohort is part of an ongoing clinical trial CRITICAL (Cockroach
Immunotherapy in Children and Adolescents;
https://clinicaltrials.gov/ct2/show/NCT03541187). Subjects were
enrolled if they were IgE sensitized to CR antigen (measured by skin
prick testing and serum IgE) and were ages 8 through 17 with
well-controlled asthma (mild-moderate persistent) at study entry
(Table 1) . Clinical characteristics and evaluation are detailed
in the online supporting information.