References
Abe, F., Nagao, T., Okabe, H. (2001). Antiproliferative constituents in plants, 7. Leaves of Clerodendron bungei  and leaves and bark of C. trichotomum . Biol. Pharm. Bull . 24, 1338-1341.
Adriani, C., Bonini, C., Iavarone, C., et al. (1981). Isolation and characterization of paulownioside, a new highly oxygenated iridoid glucoside from Paulownia tomentosa. J. Nat. Prod. 44, 739–744.
Akbay, P., Calis, I., Undeger, U. (2002). In vitro  immunomodulatory activity of verbascoside from Nepeta ucrainica  L. Phytother. Res. 16, 593-595.
Asai, T., Hara, N., Kobayashi, S., et al. (2008). Geranylated flavanones from the secretion on the surface of the immature fruits of Paulownia tomentosa. Phytochemistry 69, 1234–1241.
Backhouse, N., Delporte, C., Apablaza, C. (2008). Antinociceptive activity of Buddleja globosa  (matico) in several models of pain.J. Ethnopharmacol. 119,160-165.
Betts, J.W., Wareham, D.W., Haswell, S.J., et al. (2013). Antifungal synergy of theaflavin and epicatechin combinations against Candida albicans. J. Microbiol. Biotechnol . 23,1322–1326.
Bulzomi, P., Bolli, A., Galluzzo, P., et al. (2012). The naringenininduced proapoptotic effect in breast cancer cell lines holds out against a high bisphenol a background. IUBMB Life 64, 690–696.
Chen, C., Chen, Z., Xu, F. et al. (2013). Radio-protective effect of catalpol in cultured cells and mice. J. Radiat. Res. 54, 76–82.
Chiou, W.F., Lin, L.C., Chen, C.F. (2003). The antioxidant and free radical scavenging properties of acteoside. Chin. Pharm. J. 55, 347-353.
Cho, J.K., Curtis-Long, M.J., Lee, K.H., et al. (2013). Geranylated flavonoids displaying SARS-CoV papain-like protease inhibition from the fruits of Paulownia tomentosa. Bioorg. Med. Chem. 21, 3051–3057.
Cho, J.K., Ryu, Y.B., Curtis-Long, M.J., et al. (2012). Cholinesterase inhibitory effects of geranylated flavonoids from Paulownia tomentosa fruits. Bioorg. Med. Chem . 20, 2595–2602.
Damtoft, S. and Jensen, S.R. (1993). Tomentoside and 7-hydroxytomentoside, two iridoid glucosides from Paulownia tomentosa.Phytochem . 6, 1636-1638.
Deepak, M., Handa, S.S. (2000). Antiinflammatory activity and chemical composition of extracts of Verbena officinalis. Phytother. Res . 14, 463–465.
Dembitsky, W.M. (2005). Astonishing diversity of natural surfactants: 5. Biologically active glycosides of aromatic metabolites. Lipids40, 1081-1105.
Guan, T., Qian, Q., Tang, X., et al. (2011). Maslinic acid, a natural inhibitor of glycogen phosphorylase, reduces cerebral ischemic injury in hyperglycaemic rats by GLT-1 up-regulation. J. Neurosci. Res . 89, 1829–1839.
Jiang, T.F., Du, X., Shi, Y.P., et al. (2004). Determination of flavonoids from Paulownia tomentosa (Thunb) Steud. by micellar electrokinetic capillary electrophoresis. Chromatographia 59, 255–258
Kang, K.H., Jang, S.J., Kim, B.K., et al. (1994). Antibacterial phenylpropanoid glycosides from Paulownia tomentosa Steud. Arch. Pharm. Res. 17, 470–475.
Khachatoorian, R., Arumugaswami, V., Raychaudhuri, S. et al. (2012). Divergent antiviral effects of bioflavonoids on the hepatitis C virus life cycle. Virology 433, 346–355.
Kim, S.J., Kwon, D.Y., Kim, Y.S., et al. (2010a). Peroxyl radical scavenging capacity of extracts and isolated component from selected medicinal plants. Arch. Pharm. Res. 33, 867–873.
Kim, S.K., Cho, S.B., Moon, H.I., et al. (2010b). Neuroprotective effects of a sesquiterpene lactone and flavanones from Paulownia tomentosa Steud against glutamate-induced neurotoxicity in primary cultured rat cortical cells. Phytother. Res. 24, 1898–1900.
Kobayashi, S., Asai, T., Fujimoto, Y., et al. (2008). Anti-herbivore structures of Paulownia tomentosa: morphology, distribution, chemical constituents and changes during shoot and leaf development. Ann. Bot . 101, 1035–1047.
Lee, J.Y., Woo, E.R., Kang, K.W. (2005). Inhibition of lipopolisaccharide-inducible nitric oxide synthase expression by acteoside through blocking of AP-1 activation. J. Ethnopharmacol.97, 561-566.
Li, D.Q., Duan, Y.L., Bao, Y.M., et al. (2004). Neuroprotection of catalpol in transient global ischemia in gerbils. Neurosci. Res.50, 169–177.
Losi, G., Puia, G., Garzon, G., et al. (2004). Apigenin modulates GABAergic and glutamatergic transmission in cultured cortical neurons.Eur. J. Pharmacol. 502, 41–46.
Lu, X.Y., Li, Y.H., Xiao, X.W., Li, X.B. (2013). Inhibitory effects of luteolin on human gastric carcinoma xenografts in nude mice and its mechanism. Zhonghua. Yi. Xue. Za. Zhi . 93, 142–146.
Mankovskaia, A., Lévesque, C.M., Prakki, A. (2013). Catechinincorporated dental copolymers inhibit growth of Streptococcus mutants. J. Appl. Oral Sci. 21, 203–207.
Moneriz, G., Mestres, J., Bautista, J.M., et al. (2011). Multi-targeted activity of maslinic acid as an antimalarial natural compound.FEBS J. 278, 2951–2961.
Navrátilová, A., Schneiderová, K., Veselá, D., et al. (2013). Minor C-geranylated flavanones from Paulownia tomentosa fruits with MRSA antibacterial activity. Phytochemistry 89, 104–113.
Ota, M., Azuma, T., Onodera, S., et al. (1993). The chemistry of color changes in kiri wood (Paulownia tomentosa Steud.) III. A new caffeic acid sugar ester from Kiri wood. Mozukai Gakkaishi 39, 479–485.
Pan, J., Yuan, C., Lin, C. (2003). Pharmacological activities and mechanisms of natural phenylpropanoid glycosides. Pharmazie 58, 767-776.
Paneerselvam, M., Kawaraguchi, Y., Horikawa, Y.T., et al. (2010). Effect of epicatechin and naloxone on cardioprotective phenotype. FASEB J 24 (Meeting Abstract Supplement) 1029.8
Park KS. (2013). Aucubin, a naturally occurring iridoid glycoside inhibits TNF-a-induced inflammatory responses through suppression of NF-jB activation in 3T3-L1 adipocytes. Cytokine 62, 407–412.
Plouvier, V. (1971). The heterosides of Catalpa bignonioides Walt. (Bignoniaceae). Comp. Rend. Acad. Sci. 272, 1443–1446.
Psotova´, J., Chlopcíková, S., Miketová, P., et al. (2004). Chemoprotective effect of plant phenolics against anthracyclineinduced toxicity on rat cardiomyocytes. Part III. Apigenin, baicalelin, kaempferol, luteolin and quercetin. Phytother. Res . 18, 516–521.
Sánchez-Tena, S., Alcarraz-Viza´n, G., Marı´n, S., et al. (2013). Epicatechin gallate impairs colon cancer cell metabolic productivity.J. Agric. Food Chem. 61, 4310–4317.
Schilling, G., Hu¨gel, M., Mayer, W. (1982). Verbascoside and isoverbascoside from Paulownia tomentosa Steud. Zeit. Naturforsch . 37(B), 1633–1635.
Schinella, G., Aquila, S., Dade, M., et al. (2008). Anti-inflammatory and apoptotic activities of pomolic acid isolated from Cecropia pachystachya. Planta Med . 74, 215–220.
Schneiderová, K., Šlapetová, T., Hrabal, R., et al. (2013). Tomentomimulol and mimulone B: two new C-geranylated flavonoids from Paulownia tomentosa fruits. Nat. Prod. Res. 27, 613–618.
Senatore, F., Rigano, D., Formisano, C., et al. (2007). Phytogrowth-inhibitory and antibacterial activity of Verbascum sinuatum . Fitoterapia 78, 144-247.
Shan, J.Z., Xuan, Y.Y., Ruan, S.Q., et al. (2011). Proliferation-inhibiting and apoptosis-inducing effects of ursolic acid and oleanolic acid on multi-drug resistance cancer cells in vitro.Chin. J. Integr. Med. 17, 607–611.
Shieh, J.P., Cheng, K.C., Chung, H.H., et al. (2011). Plasma glucose lowering mechanisms of catalpol, an active principle from roots of Rehmannia glutinosa, in streptozotocin-induced diabetic rats. J. Agric. Food Chem . 59, 3747–3753.
Si, C., Deng, X., Liu, Z. (2008a). Structure and activity relationship of antioxidant flavonoids from leaves of Paulownia tomentosa var. tomentosa. In: 2nd international papermaking and environment conference, Tianjin University of Science and Technology, Tianjin, pp 263–266.
Si, C., Deng, X., Xu, Q., et al. (2008c). Characterization of phenolic acids and antioxidant activities of Paulownia tomentosa var. tomentosa leaves. In: Proceedings of the international conference on pulping, papermaking and biotechnology, pp 31–33.
Si, C.L., Deng, X.J., Liu, Z., et al. (2008b). Studies on the phenylethanoid glycosides with anti-complement activity from Paulownia tomentosa var. tomentosa wood. J. Asian Nat. Prod. Res . 10, 1003–1008.
Si, C.L., Liu, Z., Kim, J.K., et al. (2008d). Structure elucidation of phenylethanoid glycosides from Paulownia tomentosa Steud. var. tomentosa wood. Holzforschung 62, 197–200.
Si, C.L., Lu, Y.Y., Qin, P.P., et al. (2011). Phenolic extractives with chemotaxonomic significance from the bark of Paulownia tomentosa var. tomentosa. BioResources 6, 5086–5098.
Sivakumar, G., Vail, D.R., Nair, V., et al. (2009). Plant-based corosolic acid: future anti-diabetic drug? Biotechnol. J . , 1704–1711.
Šmejkal, K., Babula, P., Šlapetová, T., et al. (2008). Cytotoxic activity of C-geranyl compounds from Paulownia tomentosa fruits.Planta Med. 74, 1488–1491.
Šmejkal, K., Grycová, L., Marek, R., et al. (2007). C-geranyl compounds from Paulownia tomentosa fruits. J. Nat. Prod . 70, 1244–1248.
Sticher, O., Lahloub, M.F. (1982). Phenolic glycosides of Paulownia tomentosa bark. Planta Med. 46, 145–148.
Wilkinson, K., Boyd, J.D., Glicksman, M., et al. (2011). A high-content drug screen identifies ursolic acid as an inhibitor of amyloid-b interactions with its receptor CD36. J. Biol. Chem. 286, 34914–34922.
Wollenweber, E., Wehde, R., Christ, M., et al. (2008). Surface flavonoids in Catalpa ovata, Greyia sutherlandii and Paulownia tomentosa. Nat. Prod. Commun. 3, 1285–1287.
Xiong, Q., Hase, K., Tezuka, Y. (1999). Acteoside inhibits apoptosis in D-galactosamine and lipopolysaccharide-induced liver injury. Life Sci. 65, 421-430.
Yuan, Z.L., Luo, L., Zang, A.M., et al. (2009). Isolation and bioassay of herbicidal active ingredient from Paulownia tomentosa. Chin. J. Pestic. Sci. 2, 239–243.
Zhang, D.L., Li, X.Q. (2011). Studies on the chemical constituents from the leave of Paulownia tomentosa. Zhong Yao Cai 34, 232–234
Zhang, S.M., Coultas, K.A., (2013). Identification of plumbagin and sanquinarine as effective chemotherapeutic agents for treatment of schistosomiasis. Int. J. Parasitol. Drugs Resist. 3, 28–34.
Zhao, J., Ding, H.X., Wang, C.M. (2012). Isolation, modification and cytotoxic evaluation of flavonoids from Rhododendron hainanense.J. Pharm. Pharmacol. 1785–1792.
Zhu, Z.H., Chao, C.J., Lu, X.Y., et al. (1986). Paulownia in China: cultivation and utilization. Asian Network for Biological Science and International Development Research Centre, Chinese Academy of Forestry, Beijing. http://idl-bnc.idrc. ca/dspace/bitstream/10625/8226/1/71235.pdf.
Table 1. Calibration curves of standards