RESULTS
This study consisted of 55 cases (18 IHCP and 37 control). Comparison of
demographic features was summarized in Table 1. There was no
statistically significant difference between IHCP and control group in
terms of maternal demographic characteristics and obstetric history
except parity (p=0,02).
Umbilical artery, middle cerebral artery and pulmonary artery Doppler
flow indices were summarized in Table 2. Regarding the Doppler findings,
mean pulmonary artery AT, ET, PATET and peak systolic velocity values
were statistically significant different between the groups (p=0,001;
p=0,024 and p=0,003, respectively). The mean PATET value in the IHCP
group was 0,217 ± 0,029 while in the control group it was 0,180 ± 0,020
(p=0,003). Mean maternal serum bile acid value was 27,8 ± 16,3 mmol/L.
In Table 3, birth characteristics, umbilical venous blood gas analysis,
NICU admission and respiratory distress values were compared. The
comparisons regarding to type of delivery, administration of antenatal
corticosteroid, APGAR scores at the first and fifth minutes and
respiratory distress were not statistically significant, but gestational
age at birth and birthweight were different (p=0,001 and p:0,034). As
statistically different, lower pH values and higher pCO2values were detected in the IHC group. Acidemia was not detected in any
of them.
In the IHCP group, 8 (44,4%) newborns admitted to NICU and 5 (27,7%)
of them had respiratory distress. Besides, 3(8%) newborns in the
control group admitted to NICU due to respiratory distress. When NICU
admission and respiratory distress values were compared, NICU admission
was significantly different but respiratory distress was not found
(p:0,012 and p:0,096, respectively). APGAR score at fifth minutes,
gestational age at birth and respiratory distress were significantly
correlated with NICU admission. Moderate negative correlations between
gestational age at birth (r=-.471 p=0,001) , APGAR score at fifth
minutes (r=-.294 p=0,031) and NICU admission were found. A moderate
correlation between respiratory distress (r=,372 p:0,006) and NICU
admission was found. While PATET values were correlated with gestational
age at birth, respiratory distress and NICU admission were not
correlated with PATET.