Total Weight gain during pregnancy
In normal-weight women, total GWG was 14.6±4.7 kg for PE, 12.3±4.2 kg for DVT, 13.9±4.7 kg for all VTE and 13.2±4.3 kg for control (Table S1), and did significantly differ between PE and control group (adjusted estimated mean difference combined 0.06 kg, 95% CI 0.01-0.13 kg) (Table 2). A tendency towards decreased risk at lower total weight gain (aOR 0.85; 95% CI 0.43–1.69) and significantly increased risk at higher values (aOR=1.52; 95% CI: 1.01-2.31) for PE was observed in normal-weight women, whereas there was no clear association between total weight gain and DVT or all VTE. As for underweight and overweight women, results from the categorical model for total weight gain indicated an increased risk at both low (aOR 1.85; 95% CI 0.28–12.08 and aOR 1.23; 95% CI 0.46–3.27, respectively) and high weight gain (aOR 2.31; 95% CI 0.44–12.16 and aOR 2.13; 95% CI 0.67–6.79, respectively), but confidence intervals were wide. In addition, total GWG was not significantly associated with DVT or all VTE (Table 3).