Statistical analysis
After data collection and coding, statistical analysis was performed using GraphPad Prism 9(The authors confirm that they had obtained copyright licenses). Descriptive analysis was performed on all variables for which the data were frequency and percentage distributions, including demographic data and clinical characteristics. The mean and standard deviation (SD) for the measurement data was calculated. When comparing the mean of the samples of the two groups in the measurement data, the Unpaired t-test was used for the comparison of groups with normal distribution, and the Mann-Whitney test was used for the comparison of groups with no normal distribution. When comparing the mean of the three groups of samples in the measurement data, a pair-to-pair comparison was conducted among the three groups. A parametric test (ANOVA test) was used for comparison between groups that all obeyed normal distribution, and a non-parametric test (Kruskal-Wallis test) was used for comparison between groups that did not obey normal distribution. When analyzing the correlation of laboratory indicators, the Pearson correlation coefficient is used to calculate the bivariate correlation if both variables obey the normal distribution, and the Spearman correlation coefficient is used to calculate the bivariate correlation if some variables do not obey the normal distribution. The difference was statistically significant with P<0.05.