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The Effect of Early or Late Initiation of Long-Acting Antipsychotics on the Caregiver Burden in Schizophrenia
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  • Dilara Cirakman Kasay,
  • Ersin Hatice Karslioglu,
  • Nese Bal,
  • Ali Çayköylü
Dilara Cirakman Kasay
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Ersin Hatice Karslioglu
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Nese Bal
Ankara Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Corresponding Author:[email protected]

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Ali Çayköylü
Yildirim Beyazit University Faculty of Medicine
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Aim: Effective treatment in the early stages of schizophrenia is of critical importance to improve the prognosis. Schizophrenia affects patients’ relatives too. The effects of early or late initiation of long-acting injectable antipsychotics (LAI-APs) on the patient have been shown, yet their effects on the caregiver are still unknown. We aimed to determine how the time of initiation of LAI-APs affects the caregiver burden by comparing the patients who were started on LAI-APs in the first five years of diagnosis and those who were started in the later period. Methods: Patients were classified as ‘early-LAI’ and ‘late-LAI’ according to the time of beginning LAI. Their caregivers were also classified in the same way, as ‘caregiver-early’ and ‘caregiver-late’, and were compared in terms of caregiver burden. Results: The quality of life, depression, anxiety, and caregiver burden scores of the caregiver-late group were significantly worse. The time of initiation of LAI-APs was found to be a determinant factor for the caregiver burden. Conclusions: This is the first study to investigate the effects of LAI-Aps initiation time on the caregivers to our knowledge. Using LAI-APs in the early stages is associated with better outcomes for the caregiver.