Heat stress combined with lipopolysaccharide induces pulmonary microvascular endothelial cell glycocalyx inflammatory damage in vitro

Jiadi Chen^{1, #}, Chengjia Ding^{2, #}, Jingjing Cao², Yi Chen^{2, *}, Huasheng Tong^{3, *}

¹Department of Intensive Care Unit, First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China

²Department of Critical Care Medicine, Binhaiwan Central Hospital of Dongguan, Dongguan Hospital Affiliated to Jinan University, No. 111, Humen Avenue, Dongguan, Guangdong, 523900, China

³Department of Emergency Medicine, General Hospital of Southern Theatre Command of PLA, Guangzhou, Guangdong,510010, China

^*Correspondence: Yi Chen, Email: Chenyi_icu@163.com, TEL: 13580538400

^*Correspondence: Huasheng Tong, Email:fimmuths@163.com, TEL: 13710960796

^#Jiadi Chen and Chengjia Ding are cofirst authors.

Funding information

This research was funded by the Fundamental and Applied Basic Research Fund of Guangdong Province (No. 2019A1515011777) and Scientific Research Project of Guangdong Provincial Administration of Traditional Chinese Medicine (No. 20201369)