1A and 2A. Pre-Ablation, acute, and chronic voltage maps (0.1-1mV) of RA intercaval lines treated with LTC and HTC. 1B and 2B. Gross pathology of representative intercaval lines (outlined in dotted yellow) show areas of damage and samples of this tissue (white boxes) with Masson’s Trichrome stain demonstrate pink, healthy myocardium on unablated border regions (1C,D and 2C,D) , and transmural blue fibrosis for both LTC and HTC lesions (1E and 2E) .
Figure 5: NTC Intercaval Line A. EAM of an NTC intercaval line shows low voltage where HTC lesions were placed and high voltage where the NTC lesion was placed. Tissue treated with NTC also showed no signs of significant damage in gross pathology (C ), or in histology with Masson’s Trichrome staining (D ) while areas treated with HTC showed gross damage (C, yellow dotted line) and signs of edema and myocytolysis in histology (B).