Methods:
In ten animals, pre-ablation CTC between a novel large area focal (LAF) ablation catheter and cardiac targets was evaluated using a custom local impedance (LI) system, with guidelines established in previous pilot studies using intracardiac echocardiography (ICE), electrogram amplitude, and electroanatomic mapping (EAM) . Isolated ventricular lesions and atrial lesion sets were created with varying amounts of CTC. Treatment size and isolation of targeted structures were examined at acute and chronic timepoints using EAM and histology.