3.5 Cardiovascular activity
In many eastern countries used mulberry leaves to treat cardiovascular diseases. In china people use mulberry for decreasing blood pressure which is the main reason for the cardiovascular disorder. The mulberry leaves also helps to reduce the serum cholesterol, hypertension and to prevent artherosclerosis [61]. The cardiovascular diseases basically related to heart or blood vessels. High concentration of iron present in mulberry leaves which helps in better distribution of oxygen by boosting the production of RBCs. Reveratrol is a flavonoid present in the mulberry leaves helps in increasing the formation of nitric oxide (NO) which acts as a vasodilator. This will relaxes blood vessels and reduces the chances of blood clot formation and subsequent heart diseases like heart strokes. The resveratrol helps to remove the restrictions in blood vessels which in turn reduces the chance of heart failure [62].