Characteristics and incidence of ADR
Hospitalized patients with drug recordings from May 1, 2022 to April 30, 2023 monitored by ADE-ASAS-Ⅱ were 102430 cases in total, in which 1932 cases were warned by system, 98.11% of cases were irrelevant which could be exclude automated. We obtained 1106 positive cases as positive group after artificial evaluation, with an incidence of 1.08%. composed negative group. Flowchart for DAMAR patients’ inclusion was shown in Figure 1. Cases without warning signals or those alarmed but not evaluated as positive cases formed the negative case group. 125 cases in positive group occurred rhabdomyolysis with CK over 1000 IU/L, the incidence was 0.12%. Cases in positive group accepted surgery during hospitalization was 783 (70.80%) while 323 (29.20%) didn’t.