Clinical characteristics
The median hospitalization duration was 18 days, the occurring time of
DAMAR was concentrated in 5 days after administration, which need us
focus more on patients with relevant risk factors in the preceding days
after using muscle-toxic drugs. Increased CK value of patients followed
a skewed distribution, which might associate with some patients’ severe
damage result in rapid growth [18]. Surgery also
influences on muscle, resulting in CK increasing[19], surgery duration was considered as an
important factor of CK increasing. Our study found weak correlation
between surgery duration and CK values. Some
literature[20] reported that CK significantly increased
patients generally accompanied with surgery duration over 7 hours or
most severely obese. Few patients in our study conformed to the
situation, which might be the reason of weak correlation.