<div>
<b>Abstract:</b> The incidence of <i>Pseudomonas aeruginosa</i>
causing nosocomial infections has increased in recent years, along with
the emergence of resistant strains of bacteria causing mortality. Many
recent studies have shown increased resistance to colistin, which is the
last resort for treating multidrug-resistant <i>P. aeruginosa</i>. A
cross-sectional descriptive study and convenience sample were conducted
to determine the percentage of infections, rates of seven antibiotics,
and colistin resistance <i>in P. aeruginosa</i> strains isolated in Can
Tho Central General Hospital and relevant factors from June 2020 to
April 2021. <i>P. aeruginosa</i> infection rate was 7.9%. The specimens
contained 233 strains of <i>P. aeruginosa</i> isolated. Incident rates
in males/females were 9.3%/6.2%, the most of 19-29 years. The highest
rate was in urine specimens (9.8%) and sputum (8.8%). The male sex had
a higher infection rate than the female, and urine samples accounted for
the highest rate of <i>P. aeruginosa</i> infections (13.9%). The rate
of <i>P. aeruginosa</i> infections was associated with gender and
various species (p&lt;0.05). The prevalence of <i>P.
aeruginosa</i> infections showed an association with gender and types of
specimens (p&lt;0.05). The highest resistance rate in <i>P.
aeruginosa</i> against ciprofloxacin was 60.5%, next to gentamicin and
imipenem (52.4% and 50.2%). 3% <i>P. aeruginosa</i> against colistin.
<b>Keywords:</b> <i>Pseudomonas aeruginosa</i>; drug resistance;
<i>Pseudomonas</i> infection; colistin</div>