2.2.3 SB and AC
The GWAS summary dataset for SB and AC was extracted from GWAS and the
Sequencing Consortium of Alcohol and Nicotine use (GSCAN)
(https://genome.psych.umn.edu/index.php/GSCAN).SB represented by smoking initiation (n =1,232,091) is a binary
phenotype, indicating whether an individual had ever smoked regularly;
AC is a continuous phenotype measured with drinks per week
(n=941,280)[15].