Footnote
Author’ contributions: Fei
Jiang had full access to all the data in the study and take
responsibility for the integrity of the data and the accuracy of the
data analysis. Study concept and design: Danni Wang. Acquisition,
analysis, or interpretation of data: All authors. Drafting of the
manuscript: Fei Jiang and Danni Wang. Critical revision of the
manuscript for important intellectual content: All authors. Statistical
analysis: Fei Jiang. Obtained funding: Danni Wang. Administrative,
technical, or material support: Danni Wang. Study supervision: Danni
Wang.
Acknowledgments: The authors would like to thank the Center for
Reproductive Medicine, First Affiliated Hospital of Anhui Medical
University for their technical support for data collection. The authors
would also like to thank the study participants and staff.
Institutional Review Board Statement: The Ethics Committee of
Anhui Medical University approved the study protocols (No. 20200961).
And the study design was confirmed in accordance with the Helsinki
Declaration.
Informed Consent Statement: All participants provided informed
consent before enrollment.
Funding: This work was supported by the National Natural
Science Foundation of China (72004001), and grants from Anhui Provincial
Scientific Research and Humanities Project of Colleges and Universities
(2022AH050627).
Disclosure statement: All authors have completed the ICMJE
uniform disclosure form and have no conflicts of interest to declare.
Attestation statement: The subjects in this trial have not
concomitantly been involved in other randomized trials. Data regarding
any of the subjects in the study has not been previously published
unless specified. Data will be made available to the editors of the
journal for review or query upon request.
Data sharing statement: Data will be made available on request.
Word counting: 222 words for abstract and 3784 words for text.
Number of figures and tables : 3 tables, 2 figures, 2
supplemental tables, and 3 supplemental figures.