Data source
The data of 1023 patients who had been treated by cryoablation at Fujian
Provincial Hospital (FPH) between
April 2016 and November 2019 were
reviewed retrospectively. Patients were assessed at the 3rd, 6th,12th
months in the first year post-ablation and at 6-month intervals
thereafter with a 12-lead ECG and a 24-hour Holter ECG. Written informed
consents for tissue collection were obtained from all patients prior to
inclusion. The random forest method was adopted for interpolation when
the clinicopathological data were partially missing, and the missing
rate of the data was less than 10%. Patients were randomly divided into
training set and validation set according to the ratio of 7:2:1, of
which 716 patients were in the training set, 204 patients were in the
validation set 1 and 103 patients in the validation set 2. The primary
clinical endpoint was disease-free survival (DFS), which is from the
date of surgery to the date of recurrence, metastasis, or last
follow-up.