Data source
The data of 1023 patients who had been treated by cryoablation at Fujian Provincial Hospital (FPH) between April 2016 and November 2019 were reviewed retrospectively. Patients were assessed at the 3rd, 6th,12th months in the first year post-ablation and at 6-month intervals thereafter with a 12-lead ECG and a 24-hour Holter ECG. Written informed consents for tissue collection were obtained from all patients prior to inclusion. The random forest method was adopted for interpolation when the clinicopathological data were partially missing, and the missing rate of the data was less than 10%. Patients were randomly divided into training set and validation set according to the ratio of 7:2:1, of which 716 patients were in the training set, 204 patients were in the validation set 1 and 103 patients in the validation set 2. The primary clinical endpoint was disease-free survival (DFS), which is from the date of surgery to the date of recurrence, metastasis, or last follow-up.