Author Contributions
SG designed the study, conceived and performed experiments, analyzed data, wrote the manuscript, supervised the funding of the work, and secured the findings; AMM performed experiments, analyzed the data and wrote the manuscript; AA performed experiments and wrote the manuscript, GD acquired data, analyzed data and contributed to interpretation of the results, EA performed experiments, contributed to interpretation of the results and wrote the manuscript. TS provided expertise and feedback. MR and PELS supervised the study. All authors discussed the results and contributed to the final version of the manuscript.