CSPH risk model development
We developed a categorization model according to the method of Jiang et
al.14 Firstly, the risk factors included in CSPH
predicting model were selected from the systematic review and
meta-analysis described above. Secondly, the β-coefficient of risk
factors was calculated according to the pooled ORs and its corresponding
95% CIs, respectively. Thirdly, the score of different components was
calculated by multiplying the value of one component by the
β-coefficient. For example, the score of part of LSM was calculated by
multiplying the value of LSM by the β-coefficient of LSM. Finally, the
CSPH risk was calculated by summing the score of all components.