Model derivation cohort
The derivation cohort came from a systematic review and meta-analysis of
three prospective cohorts and three retrospective
cohorts.5-10 These six cohorts were identified by
searching the electronic databases of MEDLINE, Embase, PubMed, and Web
of Science from the time of their inception to December 1, 2022, using a
combined text and MeSH heading search strategy with the terms: “liver
stiffness”, “chronic liver diseases”, “portal hypertension”,
“elastography” and “diagnosis”. All the studies reported odds ratios
(ORs) and corresponding 95% confidence intervals (CIs) for risk
factors. A flowchart of the study selection methodology was shown in
sFigure 1.