Model validation cohorts
A total of 1,304 patients with liver cirrhosis were enrolled in the
study. In the international multicenter cross-sectional HVPG cohort,
patients were included from China, Croatia, Singapore, and Japan between
August 2021 and November 2022. Moreover, in the international
multicenter longitudinal follow-up cohort, patients were included in
China, Japan, Southern Korea, Egypt, and Singapore between January 2009
and August 2020. Besides,
patients under carvedilol
treatment based on clinical manifestation were recruited from China
between January 2018 and October 2020.