Inclusion and exclusion criteria of the study
Included studies were required to satisfy each of the following criteria: (1) the study examined the independent parameters (including liver stiffness measured by transient elastography and/or platelet count) of clinically significant portal hypertension (CSPH) and reported the odds ratios (ORs) and corresponding 95% confidence intervals (CIs) of these independent parameters; (2) measurement of the hepatic venous pressure gradient (HVPG) was used as the reference method; and (3) the study design was a prospective or retrospective cohort design.
The exclusion criteria were as follows: (1) reviews, editorials, conference abstracts, and letters; (2) studies unrelated to the topic; (3) data incomplete or no HVPG. Supplementary Figure 1. displays the study flow diagram.