An international multicenter longitudinal follow-up cohort
The inclusion criteria: (1) adult age above or equal to 18 years old;
(2) fulfilled liver cirrhosis diagnosis based on LSM, radiological,
histological or clinical features. The exclusion criteria: (1) prior
hepatic decompensation; (2) HCC; (3) prior liver transplantation; (4)
portal vein thrombosis; (5) ongoing use of antiplatelet or
anticoagulation; (6) incomplete follow-up data; (7) with NSBBs
treatment.
A longitudinal
carvedilol-treating cohort
The inclusion criteria: (1) adult age above or equal to 18 years old;
(2) fulfilled liver cirrhosis diagnosis based on LSM, radiological,
histological or clinical features; (3) high risk defined by CSPH risk
model. The exclusion criteria: (1) prior hepatic decompensation; (2)
HCC; (3) prior liver transplantation; (4) portal vein thrombosis; (5)
ongoing use of antiplatelet or anticoagulation; (6) incomplete follow-up
data.