Statistical Analysis
Patients who crossed over from BTTP to TPPM were included in their
initial treatment group, and the analysis was performed based on the
intention-to-treat principle.
Data were reported as mean + standard deviation (SD) for
continuous variables or percentage for categorical variables. Pacing
duration was reported as median (range) for better representation of
non-normal distribution. Variables were compared between the two groups
using t-tests for continuous variables and Chi-square
(c2) test for categorical variables. A multivariable
logistic regression analysis was performed to obtain the Odds Ratios
(OR) and 95% Confidence Interval (95% CI) for pre-defined outcomes,
adjusting for age, gender, and indication for a temporary pacemaker. A
sensitivity analysis was also performed to evaluate the incidence of
temporary pacemaker related adverse events in patients with TPPM based
on their in-hospital setting location. A two-tailed P value
< 0.05 was considered statistically significant. All
statistical analyses were conducted using the JMP Pro software version
14.1.0 (SAS Institute, Inc, Cary, NC) and GraphPad Prism version 9.2.0
(GraphPad Software, San Diego, CA).