Statistical Analysis
Patients who crossed over from BTTP to TPPM were included in their initial treatment group, and the analysis was performed based on the intention-to-treat principle.
Data were reported as mean + standard deviation (SD) for continuous variables or percentage for categorical variables. Pacing duration was reported as median (range) for better representation of non-normal distribution. Variables were compared between the two groups using t-tests for continuous variables and Chi-square (c2) test for categorical variables. A multivariable logistic regression analysis was performed to obtain the Odds Ratios (OR) and 95% Confidence Interval (95% CI) for pre-defined outcomes, adjusting for age, gender, and indication for a temporary pacemaker. A sensitivity analysis was also performed to evaluate the incidence of temporary pacemaker related adverse events in patients with TPPM based on their in-hospital setting location. A two-tailed P value < 0.05 was considered statistically significant. All statistical analyses were conducted using the JMP Pro software version 14.1.0 (SAS Institute, Inc, Cary, NC) and GraphPad Prism version 9.2.0 (GraphPad Software, San Diego, CA).