Abbreviations: AOR, adjusted odds ratio.CI,confidence interval.
Data are shown as adjusted OR (95% CI), adjusted for maternal age, years of education, parity, birth place, pre-pregnancy body mass index and TG level in early pregnancy. Figure 1 Flowchart of the study population Figure 2 Heatmap of Absolute Risk for Preeclampsia Legends: Values represent the absolute risks of preeclampsia (A & C) and the percentages of participants (B & D) for the combination of body mass index and blood pressure, and the combination of TG levels and blood pressure. The absolute risk (panel A) was calculated as No. of participants (preeclampsia)/No. of participants (body mass index and blood pressure category)*100. The absolute risk (panel C) was calculated as No. of participants (preeclampsia)/No. of participants (TG levels and blood pressure category)*100. The percentages of participants were calculated as the number of participants with either combination as a percentage of the total study sample. The total study sample size is 78,016. Figure 3 Impact of risk factors on the association between maternal BP in early pregnancy and risks of PE Absolute risk differences were calculated as the difference between the risks of different blood pressures in each category of mTG and BMI. Adjusted odds ratios were shown for the association of blood pressure and the risks of PE, and all analyses were adjusted for maternal age, years of education, parity and birth place. Body mass index and maternal TG levels were stratified by the threshold of 25 and 90th quartile, respectively. The reference group was women with normal blood pressure, whose BMI < 25 and mTG < 90th quartile. The total number of women in the study were represented as the sample size to assess the outcomes. Risk differences, adjusted odds ratios, and each corresponding 95% CIs were calculated from the results of multivariable models and adjusted for baseline risk imprecision.