Data are shown as adjusted OR (95% CI), adjusted for maternal age,
years of education, parity, birth place, pre-pregnancy body mass index
and TG level in early pregnancy.
Figure 1 Flowchart of the study population
Figure 2 Heatmap of Absolute Risk for Preeclampsia
Legends: Values represent the absolute risks of preeclampsia (A & C)
and the percentages of participants (B & D) for the combination of body
mass index and blood pressure, and the combination of TG levels and
blood pressure. The absolute risk (panel A) was calculated as No. of
participants (preeclampsia)/No. of participants (body mass index and
blood pressure category)*100. The absolute risk (panel C) was calculated
as No. of participants (preeclampsia)/No. of participants (TG levels and
blood pressure category)*100. The percentages of participants were
calculated as the number of participants with either combination as a
percentage of the total study sample. The total study sample size is
78,016.
Figure 3 Impact of risk factors on the association between
maternal BP in early pregnancy and risks of PE
Absolute risk differences were calculated as the difference between the
risks of different blood pressures in each category of mTG and BMI.
Adjusted odds ratios were shown for the association of blood pressure
and the risks of PE, and all analyses were adjusted for maternal age,
years of education, parity and birth place. Body mass index and maternal
TG levels were stratified by the threshold of 25 and
90th quartile, respectively. The reference group was
women with normal blood pressure, whose BMI < 25 and mTG
< 90th quartile. The total number of women
in the study were represented as the sample size to assess the outcomes.
Risk differences, adjusted odds ratios, and each corresponding 95% CIs
were calculated from the results of multivariable models and adjusted
for baseline risk imprecision.
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