Conclusion
In summary, our study found that elevated blood pressure, stage 1 and
stage 2 hypertension diagnosed based on 2017 ACC/AHA criteria increase
the risks of preeclampsia, especially the latter two. Obesity and
elevated TG serum concentrations were two independent risk factors for
developing preeclampsia (data not shown), and they tended to strengthen
the association between the new BP categories and the risk of developing
preeclampsia, especially in stage 1 and stage 2 hypertension. The
results would add value to the clinical practice that clinicians should
pay more attention and raise the necessity of intervention to women with
stage 1/2 hypertension at <20 weeks gestation under the
condition of overweight/obesity and high TG in identifying women at
heightened risk for preeclampsia.
Author contributions: Drs Lin and Wu had full access to all of
the data in the study and take responsibility for the integrity of the
data and the accuracy of its analysis.
Concept and design: Huang, Lin and Wu.
Acquisition, analysis and interpretation of data: All authors.
Drafting of the manuscript: Wu, Lin.
Critical revision of the manuscript for important intellectual
content: All authors.
Statistical analysis: Wu, Lin and Wei.
Obtained funding: Huang, Lin and Wu.
Administrative, technical, or material support: Wu, Lin, Huang.
Supervision: Lin, Huang.
Conflict of interest disclosures: No disclosures to report.
Data sharing statement: The dataset generated from the study is
available on request to the corresponding author.