Figure 5. Blood calcium levels are negatively correlated with
the severity of PQ poisoning. (A-B) A retrospective analysis of the
correlation between PQ and blood calcium levels. (A) Mean ± s.d., ***P
< 0.001; unpaired two–tailed Student’s t–test. n = 22 in
healthy group, n= 18 in PQ group. (B) Pearson correlation coefficient. n
= 22. (C-E) The correlation between PQ and levels of blood
potassium (K+, C), sodium (Na+, D)
or chloride (Cl-, E). (F&G) Analysis of
blood calcium levels and blood creatinine levels in each PQ-poisoned
patient during disease progression. (H) Levels of serum calcium
levels in PQ-poisoned mice treated w/wo lysine for 3 days. (I)Levels of blood calcium in PQ-poisoned cynomolgus monkey treated w/wo
lysine for 3 days. Arrows indicate lysine treatment.