Aminoglycoside
N-acetyltransferase
|
MtAAC(2’)-Ic
|
M. tuberculosis
|
Aminoglycosides
|
Antibiotic resistance
|
Barrett et al., 2008
|
|
EfAAC(6’)-Ii |
Enterococcus faecium |
|
|
Hegde et al., 2002;
Magnet et al., 2001; Wright & Ladak,1997 |
|
SeAAC(6’)Ie |
Salmonella enterica |
|
|
|
|
MtbEis |
M. tuberculosis |
Aminoglycosides |
Antibiotic
resistance |
Chen et al., 2011; Houghton et al., 2013; Zaunbrecher et
al., 2009; |
Spermidine/spermine N-acetyltransferase
|
BltD
|
B. subtilis
|
Polyamines
(spermidine
/spermine)
|
Unknown
|
Woolridge et al., 1999
|
|
PaiA |
B. subtilis |
|
|
Forouhar et al., 2005 |
|
SpeG |
Vibrio cholerae |
|
Possibly involved in biofilm
formation |
Filippova et al., 2015 |
|
|
Staphylococcus aureus |
|
|
Li et al., 2019 |
|
|
E. coli |
|
Inhibition of spermidine accumulation |
Fukuchi
et al., 1995; Limsuwun & Jones, 2000 |
|
|
Bacillus thuringiensis |
|
Unknown |
Tsimbalyuk et al.,
2020 |
|
Ste26 |
Streptomyces sp. |
|
Unknown |
Bai et al.,
2011 |
|
PmvE
|
Enterococcus faecalis
|
Putrescine/spermine
|
Contributes to the virulence of the bacteria.
Possibly involved in biofilm formation
|
Martini et al., 2015
|
Lysine Nε-acyltransferase |
MtRv1347c |
M. tuberculosis |
Fatty
acyl-CoA with longer chain lengths |
Possible role in siderophore
biosynthesis (mycobactin T) |
Card et al., 2005; Christensen et
al., 2019; Frankel & Blanchard, 2008; Hentchel & Escalante-Semerena,
2015; |
Non-histone protein
N-acetyltransferases
|
YfiQ and its homologs
|
E. coli, Vibrio cholerae, Salmonella entérica, Yersinia pestis,
Rhodopseudomonas palustris, Streptomyces lividans, and
Streptomyces
griseus
|
Acetyl-CoA synthetase
|
Loss of enzyme activity
|
Starai et al., 2004
|
|
MSMEG_5458 |
M. tuberculosis |
|
|
Xu, et al.,
2011 |
|
PA4794 |
P. aeruginosa |
C-terminal lysine residue of a peptide |
No reported |
Majorek et al., 2013 |
|
MtbEis
|
M. tuberculosis
|
Nucleoid-associated
protein
(MtHU)
|
May cause reduced interaction with DNA and altered DNA compaction
ability of nucleoid-associated proteins
|
Ghosh et al., 2016
|
|
|
|
Dual-specificity
protein phosphatase 16/mitogen-activated protein kinase phosphatase-7
(DUSP16/MKP-7)
|
Inhibition of JNK-dependent
autophagy, phagosome maturation, and ROS generation
|
Kim et al., 2012
|