Family Name Bacteria Substrate Effect Reference
Aminoglycoside N-acetyltransferase
MtAAC(2’)-Ic
M. tuberculosis
Aminoglycosides
Antibiotic resistance
Barrett et al., 2008
EfAAC(6’)-Ii Enterococcus faecium Hegde et al., 2002; Magnet et al., 2001; Wright & Ladak,1997
SeAAC(6’)Ie Salmonella enterica
MtbEis M. tuberculosis Aminoglycosides Antibiotic resistance Chen et al., 2011; Houghton et al., 2013; Zaunbrecher et al., 2009;
Spermidine/spermine N-acetyltransferase
BltD
B. subtilis
Polyamines (spermidine /spermine)
Unknown
Woolridge et al., 1999
PaiA B. subtilis Forouhar et al., 2005
SpeG Vibrio cholerae Possibly involved in biofilm formation Filippova et al., 2015
Staphylococcus aureus Li et al., 2019
E. coli Inhibition of spermidine accumulation Fukuchi et al., 1995; Limsuwun & Jones, 2000
Bacillus thuringiensis Unknown Tsimbalyuk et al., 2020
Ste26 Streptomyces sp. Unknown Bai et al., 2011
PmvE
Enterococcus faecalis
Putrescine/spermine
Contributes to the virulence of the bacteria. Possibly involved in biofilm formation
Martini et al., 2015
Lysine Nε-acyltransferase MtRv1347c M. tuberculosis Fatty acyl-CoA with longer chain lengths Possible role in siderophore biosynthesis (mycobactin T) Card et al., 2005; Christensen et al., 2019; Frankel & Blanchard, 2008; Hentchel & Escalante-Semerena, 2015;
Non-histone protein N-acetyltransferases
YfiQ and its homologs
E. coli, Vibrio cholerae, Salmonella entérica, Yersinia pestis, Rhodopseudomonas palustris, Streptomyces lividans, and Streptomyces griseus
Acetyl-CoA synthetase
Loss of enzyme activity
Starai et al., 2004
MSMEG_5458 M. tuberculosis Xu, et al., 2011
PA4794 P. aeruginosa C-terminal lysine residue of a peptide No reported Majorek et al., 2013
MtbEis
M. tuberculosis
Nucleoid-associated protein (MtHU)
May cause reduced interaction with DNA and altered DNA compaction ability of nucleoid-associated proteins
Ghosh et al., 2016
Dual-specificity protein phosphatase 16/mitogen-activated protein kinase phosphatase-7 (DUSP16/MKP-7) Inhibition of JNK-dependent autophagy, phagosome maturation, and ROS generation
Kim et al., 2012