Figure 4 (A) Fluorescence spectra of TGC, CDs, CDs with TGC;
(B) Fluorescence spectra of CDs with different concentrations of
tigecycline; (C) Linear relationship between the fluorescence intensity
of CDs and concentrations of tigecycline; (D) Effect of various
coexisting ions and compounds on the fluorescence intensity of CDs; (E)
Fluorescence intensity of CDs by introducing other antibiotics; (F)
UV-vis spectrum of TGC and fluorescence spectra of CDs; (G) UV-vis
spectra of CDs, TGC and CDs with TGC; (H) Fluorescence lifetime decays
of CDs without or with TGC; (I) FTIR pattern of TGC and CDs with TGC.
4. Conclusions
In summary, the long-emission CDs with the yellow fluorescence were
originated synthesized. To be specific, the fluorescence intensity of
CDs gradually decreased with pH decreasing in the acidic range, which
was owing to the changed surface state of CDs, and thus these CDs showed
the potential for pH sensing. Importantly, introducing tigecycline into
the CDs obviously quenched their fluorescence based on the mechanism of
the static quenching, thus an innovative method of detecting the
tigecycline was successfully established. Moreover, the practicality of
this assay was verified by examining the lake water samples supplemented
with tigecycline. Consequently, the proposed strategy established here
may broaden the ways for assaying tigecycline towards the multiple
purposes.
Acknowledgement
This work was supported by Natural Science Foundation of Chongqing,
China (cstc2021jcyj-msxmX0027), Talent and Innovation Project of Beibei
District in Chongqing (2022-11), Performance Incentive and Guidance
Special Project of Scientific Research Organization, Chongqing Science
and Technology (cstc2021jxjl130024).
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