Key points:
・ There have been a few reports on the surgical outcomes of
phosphaturic mesenchymal tumors causing tumor-induced osteomalacia in
the head and neck.
・Tumor-induced osteomalacia is a rare and underreported condition
because treating clinicians are unaware of its clinical characteristics.
We highlighted our experience with Tumor-induced osteomalacia cases in
the head and neck regions.
・Phosphaturic mesenchymal tumor resection in the head and neck region
was associated with high local recurrence/residual disease rate.
・Before definitive resection, surgeons should discuss with their
patients the difficulty of obtaining clear margins due to the complex
anatomy.
・Re-excision lead to biological remission in the majority of the
patients after re-excision.