Figure 2
Aldosterone infusion promotes immune cell infiltration in the brain. A: Aldosterone-induced hypertension (n=8). All data are mean ± S.E.M. *P<0.05. Two-way ANOVA with Tukey’s test. B:Representative flow cytometry dot plots showing gating strategy for microglia (CD45+ low) and total leukocytes (CD45+ high) from the brains of mice infused with vehicle or aldosterone. The effect of aldosterone infusion on C: CD45+low microglia,D: CD45+ leukocytes, E: CD3+ T cells, F: CD4+ T cells, G: CD11b+ myeloid cells and H: F4/80+ macrophages in the brain (n=8). All data are mean ± S.E.M. *P<0.05. Student’s unpaired t-test.