Furthermore, we run a second suite of tests to compare the highest risk
variants (\(j\) = 4) used in the first section against the true
frequencies of SCZ and BPD in Canada. We assume that these variants
have a 100% certainty of causing a SCZ or BPD diagnosis if present in
an individual’s genome. The age and sex distributions of SCZ and BPD
classified by gnomAD are noted, constrained by ages <30,
50–55, and >80. Fig. \ref{628883} demonstrates the age and
sex brackets in Canada and those of gnomAD for BPD.