Histology
Electron bronchoscopy and ultrasound-guided fine-needle aspiration biopsy of the left supraclavicular lymph node were conducted to obtain tissue samples from the lung and left supraclavicular area, respectively. In the tissue from the posterior segment of the right upper lobe of the lung, a few clusters of atypical cells arranged in a glandular pattern were visible, with observable mitotic figures. This finding suggests the presence of adenocarcinoma (figure 5).
The needle biopsy specimen from the fibrous connective tissue of the left supraclavicular region revealed metastatic adenocarcinoma (figure 6). Immunohistochemistry displayed a CK7+ and CK20-, TTF-1-, and NapsinA- profile, with a Ki-67 positive rate of approximately 10%.
These findings are consistent with a diagnosis of metastatic lung cancer.