3.5 Predictions of clinical outcomes
A total of 1550 PAH patients were included in logistic regression
analyses after excluding the patients with concomitant use of
PAH-specific vasodilators targeting the same biological pathways. Table
3 demonstrates the univariate and multivariate logistic regression
models that estimate clinical outcomes (death or non-death) of the PAH
patients reported in the JADER database. The multivariate model with the
interaction term between epoprostenol and warfarin had lower AIC than
without the interaction term. The area under the ROC curve of the final
model was 0.668. Supplementary Table S3 summarizes the ORs of all
variables in the univariate analyses.