Palladium-catalyzed denitrogenative self-carbonylation of arylhydrazine using CO and O2 as an ideal oxidant Yuvraj A. Kolekar, a and Bhalchandra M. Bhanage *, a Chin. J. Chem. 2022, 40, XXX—XXX. DOI: 10.1002/cjoc.202200XXX
Pd/Cu-catalyzed denitrogenative self-carbonylation of arylhydrazine hydrochlorides to synthesize symmetrical biaryl ketones under CO/O2 pressure has been developed. The arylhydrazine hydrochlorides are used as a green arylating agent which releases nitrogen and water as a byproduct. This developed protocol significantly restricts the formation of aryl iodide and azobenzene products even under favorable conditions. Additionally, this protocol provides a series of symmetric carbonylative ketones with a wide variety of functional group tolerance under CO/O2 pressure. .