Figure 6. Evaluation of NE-A1AT complex in the plasma samples by
ELISA.
The levels of NE-A1AT complexes were found significantly higher in
COVID-19 patients compared to healthy individuals.
Figure S1 Pathological lesions of alveolitis, bronchiolitis,
inflammation thrombosis and pleuritic in COVID-19. (A) Alveolar
epithelial denudation is evident by H&E staining (open arrow). (B)
Extensive bronchiolitis with sloughing of bronchiolar epithelium was
noted in all cases (black arrow). (C) Denudation of epithelial lining
and formation of hyaline membranes in COVID-19 patients (black
arrowhead), (D) edema with filling of alveolar air spaces with protein
exudates (asterisks), (E) One specimen showed evidence of pleuritic
(yellow frame). (F) In two cases, bacterial superinfections were noted
with presence of bacterial colonies admixed with neutrophils within the
alveoli (hash). (G) Blood vessels also show prominent fibrin thrombus.
(H- I) Perivascular regions showing loosely proliferating fibroblasts,
accumulation of collagen, and (H) degradation of elastin fibers (red
arrows). Scale bar=100 μm.