Figure 6. Evaluation of NE-A1AT complex in the plasma samples by ELISA.
The levels of NE-A1AT complexes were found significantly higher in COVID-19 patients compared to healthy individuals.
Figure S1 Pathological lesions of alveolitis, bronchiolitis, inflammation thrombosis and pleuritic in COVID-19. (A) Alveolar epithelial denudation is evident by H&E staining (open arrow). (B) Extensive bronchiolitis with sloughing of bronchiolar epithelium was noted in all cases (black arrow). (C) Denudation of epithelial lining and formation of hyaline membranes in COVID-19 patients (black arrowhead), (D) edema with filling of alveolar air spaces with protein exudates (asterisks), (E) One specimen showed evidence of pleuritic (yellow frame). (F) In two cases, bacterial superinfections were noted with presence of bacterial colonies admixed with neutrophils within the alveoli (hash). (G) Blood vessels also show prominent fibrin thrombus. (H- I) Perivascular regions showing loosely proliferating fibroblasts, accumulation of collagen, and (H) degradation of elastin fibers (red arrows). Scale bar=100 μm.