Statin use and the risk of Parkinson’s disease in persons with diabetes: A nested case-control study
Short title: Statins and risk of PD
Kim Honkamaa, MSc1, Anne Paakinaho, MSc1,2, Anna-Maija Tolppanen, PhD1,2, Raimo Kettunen, MD, PhD3, Sirpa Hartikainen, MD, PhD2, Miia Tiihonen, PhD1,2
1School of Pharmacy, University of Eastern Finland, Kuopio, Finland
2Kuopio Research Centre of Geriatric Care, University of Eastern Finland, Kuopio, Finland
3School of Medicine, University of Eastern Finland, Kuopio, Finland
Corresponding author
Miia Tiihonen, PhD, Docent, Senior Researcher
School of Pharmacy, University of Eastern Finland, PL1627, 70211 Kuopio, Finland. Tel +35850 575 9530, Fax Tel +35817 162424, email miia.tiihonen@uef.fi
Keywords: Statins, Parkinson’s disease, Diabetes
Word count: 2404
Table count: 4
Figure count: 1
What is already known about this subject: Both diabetes and statins could modify the risk of Parkinson’s disease.
What this study adds: After controlling for diabetes duration and reverse causality this study does not provide support for the hypothesis that statin use decreases the risk of Parkinson’s disease.