3.3.3 Within CU group analyses between emotional cue-induced activation of the regions of interest and cocaine use characteristics
The relationship between years of regular use and emotional cue reactivity in the VS (p = .013, η2 = .13) and dACC (p = < .01, η2 = .16) was significantly moderated by sex (p = .013, η2 = .13). Follow-up regression analyses demonstrated that emotional cue reactivity in the dACC was significantly and negatively associated with years of regular use in female CUs (B = -.47, p = .02), but positively in male CUs (B = .38, p = .08) (see Fig. 3C). Similarly, emotional cue reactivity in the VS was significantly and negatively related to years of regular use in female CUs (B = -.54,p = .002), but positively in male CUs (B = .28, p = .20) (see Fig. 3D).