Figure 2
Note. A. There were no main effects of cocaine cues versus neutral cues on activation in the regions of interests. B. Self-reported craving significantly increased following cocaine cues versus neutral cues in CUs, but not in non-CUs. There were no group or sex effects on cocaine cue induced negative affect. Cocaine cue reactivity in the dorsal striatum (C) and amygdala (D) was positively associated with cocaine use severity (DUDIT scores) in female CUs, while this relation was negative in male CUs.