|
|
HR(95% CI) |
HR(95% CI) |
HR(95% CI) |
P value |
P value |
P
value |
|
HR(95% CI) |
HR(95% CI) |
HR(95% CI) |
HR(95% CI) |
HR(95% CI) |
P value |
P value |
Sex |
Sex |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Male |
Male |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
NA |
|
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
Female |
Female |
0.67(0.57,0.80) |
0.67(0.57,0.80) |
0.67(0.57,0.80) |
<0.001 |
<0.001 |
<0.001 |
|
0.66(0.55,0.79) |
0.66(0.55,0.79) |
0.66(0.55,0.79) |
0.66(0.55,0.79) |
0.66(0.55,0.79) |
<0.001 |
<0.001 |
Age(year) |
Age(year) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
40- |
40- |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
NA |
|
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
40-50 |
40-50 |
1.29(0.98,1.70) |
1.29(0.98,1.70) |
1.29(0.98,1.70) |
0.07 |
0.07 |
0.07 |
|
1.34(1.01,1.76) |
1.34(1.01,1.76) |
1.34(1.01,1.76) |
1.34(1.01,1.76) |
1.34(1.01,1.76) |
0.06 |
0.06 |
50-60 |
50-60 |
2.56(1.94,3.38) |
2.56(1.94,3.38) |
2.56(1.94,3.38) |
<0.001 |
<0.001 |
<0.001 |
|
2.69(2.03-3.56) |
2.69(2.03-3.56) |
2.69(2.03-3.56) |
2.69(2.03-3.56) |
2.69(2.03-3.56) |
<0.001 |
<0.001 |
Marital Status |
Marital Status |
Marital Status |
Marital Status |
|
|
|
|
|
|
|
|
|
|
|
|
Married |
Married |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
NA |
|
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
Sig/window |
Sig/window |
1.41(1.18,1.70) |
1.41(1.18,1.70) |
1.41(1.18,1.70) |
<0.001 |
<0.001 |
<0.001 |
|
1.26(1.04,1.52) |
1.26(1.04,1.52) |
1.26(1.04,1.52) |
1.26(1.04,1.52) |
1.26(1.04,1.52) |
0.02 |
0.02 |
Educational Status |
Educational Status |
Educational Status |
Educational Status |
Educational Status |
|
|
|
|
|
|
|
|
|
|
|
≤6years |
≤6years |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
NA |
|
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
>6years |
>6years |
0.79(0.66,0.95) |
0.79(0.66,0.95) |
0.79(0.66,0.95) |
0.01 |
0.01 |
0.01 |
|
0.78(0.65,0.94) |
0.78(0.65,0.94) |
0.78(0.65,0.94) |
0.78(0.65,0.94) |
0.78(0.65,0.94) |
0.01 |
0.01 |
Chinese Medicine Therapy |
Chinese Medicine Therapy |
Chinese Medicine
Therapy |
Chinese Medicine Therapy |
Chinese Medicine Therapy |
|
|
|
|
|
|
|
|
|
|
|
No |
No |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
NA |
|
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
Yes |
Yes |
0.75(0.59,0.95) |
0.75(0.59,0.95) |
0.75(0.59,0.95) |
0.02 |
0.02 |
0.02 |
|
0.75(0.52,0.96) |
0.75(0.52,0.96) |
0.75(0.52,0.96) |
0.75(0.52,0.96) |
0.75(0.52,0.96) |
0.02 |
0.02 |
CD4+ Cell Count (cells/µl) |
CD4+ Cell Count (cells/µl) |
CD4+ Cell
Count (cells/µl) |
CD4+ Cell Count (cells/µl) |
CD4+ Cell Count
(cells/µl) |
|
|
|
|
|
|
|
|
|
|
|
500+ |
500+ |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
NA |
|
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
350-500 |
350-500 |
1.01(0.73,1.39) |
1.01(0.73,1.39) |
1.01(0.73,1.39) |
0.95 |
0.95 |
0.95 |
|
1.04(0.76, 1.44) |
1.04(0.76, 1.44) |
1.04(0.76, 1.44) |
1.04(0.76, 1.44) |
1.04(0.76, 1.44) |
0.80 |
0.80 |
200-350 |
200-350 |
1.39(1.05,1.84) |
1.39(1.05,1.84) |
1.39(1.05,1.84) |
0.02 |
0.02 |
0.02 |
|
1.37(1.03,1.82) |
1.37(1.03,1.82) |
1.37(1.03,1.82) |
1.37(1.03,1.82) |
1.37(1.03,1.82) |
0.03 |
0.03 |
200- |
200- |
1.89(1.44,2.48) |
1.89(1.44,2.48) |
1.89(1.44,2.48) |
<0.001 |
<0.001 |
<0.001 |
|
1.94(1.47,2.55) |
1.94(1.47,2.55) |
1.94(1.47,2.55) |
1.94(1.47,2.55) |
1.94(1.47,2.55) |
<0.001 |
<0.001 |
Liver Injury |
Liver Injury |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
No |
No |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
NA |
|
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
Yes |
Yes |
1.50(1.13,1.99) |
1.50(1.13,1.99) |
1.50(1.13,1.99) |
0.01 |
0.01 |
0.01 |
|
1.58(1.19,2.10) |
1.58(1.19,2.10) |
1.58(1.19,2.10) |
1.58(1.19,2.10) |
1.58(1.19,2.10) |
<0.001 |
<0.001 |
Unclear |
Unclear |
1.25(1.03,1.51) |
1.25(1.03,1.51) |
1.25(1.03,1.51) |
0.03 |
0.03 |
0.03 |
|
1.19(0.98,1.45) |
1.19(0.98,1.45) |
1.19(0.98,1.45) |
1.19(0.98,1.45) |
1.19(0.98,1.45) |
0.08 |
0.08 |
Factors Not Selected |
Factors Not Selected |
Factors Not Selected |
Factors Not Selected |
Factors Not Selected |
Factors Not Selected |
Factors Not Selected |
Factors Not Selected |
Factors Not Selected |
Factors Not Selected |
Factors Not Selected |
Factors Not Selected |
Factors Not Selected |
Factors Not Selected |
Factors Not
Selected |
|
HIV transmission mode |
HIV transmission mode |
HIV transmission mode |
HIV transmission mode |
HIV transmission mode |
|
|
|
|
|
|
|
|
|
|
|
Others |
Others |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
NA |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
Plasma |
Plasma |
1.17(0.93,1.47) |
1.17(0.93,1.47) |
1.17(0.93,1.47) |
0.17 |
0.17 |
0.17 |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
Time on HIV positive (year) |
Time on HIV positive (year) |
Time on HIV
positive (year) |
|
|
|
|
|
|
|
|
|
|
|
|
|
<5 |
<5 |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
NA |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
5-8 |
5-8 |
0.93(0.74,1.18) |
0.93(0.74,1.18) |
0.93(0.74,1.18) |
0.56 |
0.56 |
0.56 |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
>8 |
>8 |
0.82(0.63,1.08) |
0.82(0.63,1.08) |
0.82(0.63,1.08) |
0.16 |
0.16 |
0.16 |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
Time on ART before Second-line (year) |
Time on ART before Second-line
(year) |
Time on ART before Second-line (year) |
Time on ART before
Second-line (year) |
Time on ART before Second-line (year) |
|
|
|
|
|
|
|
|
|
|
|
<3 |
<3 |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
NA |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
3-6 |
3-6 |
0.85(0.67,1.07) |
0.85(0.67,1.07) |
0.85(0.67,1.07) |
0.17 |
0.17 |
0.17 |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
>6 |
>6 |
0.95(0.77,1.18) |
0.95(0.77,1.18) |
0.95(0.77,1.18) |
0.64 |
0.64 |
0.64 |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
Anemia |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Yes |
Yes |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
NA |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
No |
No |
1.04(0.79,1.37) |
1.04(0.79,1.37) |
1.04(0.79,1.37) |
0.80 |
0.80 |
0.80 |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
Unclear |
Unclear |
1.24(0.94,1.62) |
1.24(0.94,1.62) |
1.24(0.94,1.62) |
0.12 |
0.12 |
0.12 |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
Hyperlipidemia |
Hyperlipidemia |
|
|
|
|
|
|
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
Yes |
Yes |
1[Reference] |
1[Reference] |
1[Reference] |
NA |
NA |
NA |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
No |
No |
0.84(0.63,1.12) |
0.84(0.63,1.12) |
0.84(0.63,1.12) |
0.24 |
0.24 |
0.24 |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |
Unclear |
Unclear |
1.05(0.80,1.39) |
1.05(0.80,1.39) |
1.05(0.80,1.39) |
0.72 |
0.72 |
0.72 |
|
NA |
NA |
NA |
NA |
NA |
NA |
NA |