Risk of COVID-19 Disease Severity with Blood Type
Crude and adjusted analyses showed that ABO blood type significantly predicted the risk of COVID-19 severity (Table 4). Adjusted analyses, upon controlling age and COVID-19 vaccination, revealed that blood type A was 52% and 25% at greater risk for developing asymptomatic-to-mild (aRR=1·52, p =0·040) and severe-to-critical COVID-19 (aRR=1·25,p =0·041), respectively. Blood type AB, on the other hand, was 62% at higher risk for moderate COVID-19 (aRR=1·62, p =0·037) compared to non-AB blood type. Interestingly, those with blood type O (aRR=0·65, p =0·010) have a lower risk for moderate COVID-19 by 54%.
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