Author Contributions
MGD and KCR designed the study. Sample collection was facilitated and performed by MGD, NJB, DSN, JCH, HLG, TWS, MSW, TBS, PPM, and KCR. Laboratory work was performed by CER and TMS. MGD performed the bioinformatics data generation. CMB provided bioinformatics support and data management. ECA contributed to the population assignment study design. MGD and JFS performed the data analysis. MGD and CMB generated the figures of the manuscript. MGD and KCR wrote the paper and all authors edited and provided feedback to manuscript drafts.