Contributions
MEP, ES, LHT, MG and HP: Designed the experiments; MEP, ES, LHT, and MG: Performed experiments and collected data; LHT, MG, MA, AFS, BA and HP: Discussed the results and strategy; MA, AFS, BA and HP: Supervised, directed and managed the study; MEP, ES, LHT, MG, MA, AFS, BA and HP: All authors have seen the final version of the paper.