Index reaction
Patients’ mean age of index reaction was 5.8 years (standard deviation (SD) 4.6, range 0.2-17), being significantly lower in patients describing peanut reactions (4.6 years (SD 3.5, range 0.2-17 years), comparing with patients describing TN reactions (6.7 years, SD 5.8, range 0.2-17 years) (p=0.02) (Table 1) .
Index reaction manifestations were more frequently cutaneous (n=45, 46%), with urticaria/angioedema in 38 (84%) children and eczema exacerbation in 7 (16%). Thirty-five (36%) patients described a reaction compatible with anaphylaxis. Gastrointestinal symptoms were reported by 16 (16%) patients, of whom 9 (56%) oral allergy syndrome, 5 (31%) nausea and vomiting and 2 (13%) abdominal pain. Lastly, 2 (2%) patients presented shortness of breath (Figure 1) .