Artificial inert support
Baños et al.(Baños, Tomasini et al. 2009) used high-density polyurethane foam (PUF) as an inert support to produce lovastatin by SSF. Results showed that the titer of lovastatin in PUF solid-state fermentation is two-fold higher than that of the known solid-state fermentation system of bagasse. And the titer of lovastatin on PUF is more than 15-fold higher than that of submerged fermentation.