HLA docking results
Matched best peptide
(identical, antigenic, non-allergenic, non-toxic, IL-4 inducer, and
IFN-gamma inducer, non-IL-10 inducer, and high affinity to TAP) docked
for affinity to Class-I and Class-II MHC molecules. The MHC-I docking
results show DEDDSEPV sequence has a high affinity to HLA-A*0101,
HLA-A*0201, HLA-A*2402, HLA-B*0702, HLA-B*2705, HLA-B*5101, and
HLA-B*5801. Table-5 shows Gibbs free energy calculation and
Kd values of docking results. Figure-1 shows docked
models of DEDDSEPV and HLA subtypes.
Table-5
Results of the calculation of ΔG and Kd values of DEDDSEPV sequence
affinities to common HLA subtypes.