AUTHOR CONTRIBUTIONS
Conceived and designed the proposal: Lili Zheng, Ke Li and Wenhui liu. Performed the experiments: Lili Zheng, Jieyu Qi, Shuangfeng Chen, Ke Li and Wenhui liu.. Participated in analyzing the data: Lili Zheng, Jieyu Qi, Liyuan Zheng, Shuangfeng Chen. Wrote and revised the manuscript: Lili Zheng, Ke Li and Wenhui liu. All authors have read and approved the final manuscript.