2.3. Inclusion and Exclusion Criteria
The inclusion criteria were age range between 18 and 90 years, being hospitalized, patients with COVID-19, not being hospitalized in the intensive care unit at the time of entrance to the study, patients without coagulopathy, patients without a history of stroke, ocular and cerebral hemorrhage, women those were not pregnant or breastfeeding, patients without cancer, porphyria, liver and renal dysfunction, having no massive surgery in the past two weeks, history of intolerance or allergy to PTX or any type of Xanthine.
Exclusion criteria were the occurrence of any bleeding or severe side effects during the study such as gastrointestinal intolerance that does not respond to predetermined measures of antidote use, skin drug reactions, heart attack and stroke during the study, unstable vital signs, being intubated under mechanical ventilation, hospitalization in ICU, and patients under the treatment with any therapeutic blood thinner.