Graphical Abstract Text
The presence of a non-conditioned unfamiliar same-sex rat completely
ameliorates conditioned fear responses to an auditory conditioned
stimulus in rats. The present study demonstrated that naloxone (but not
haloperidol, SR49059, or atosiban) blocks this social buffering of
conditioned fear responses. The blockade of social buffering was
accompanied by decreased c-Fos expression in the nucleus accumbens,
anterior cingulate cortex, and insular cortex.