Figure 2. Downregulation of circ_0001722 suppresses cell proliferation of human OS cells. a: circ_0001722 is down-regulated by exogenous shRNA (sh-circ_0001722) in two human OS cell lines. b: Down-regulation of circ_0001722 can suppress cell proliferation of both human OS cell linesin vitro . c: Downregulation of circ_0001722 can suppress the invasion ability of both human OS cell lines. d: Downregulation of circ_0001722 can suppress cell proliferation of MG63 cellsin vivo .P <0.05.P <0.01.