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\begin{document}

\title{Science AMA Series: We're Drs. Paul Oberstein and Manji Gulam, GI Cancer
Specialists at Columbia University focusing on the use of personalized
medicine to fight cancer. Ask us Anything!}



\author[1]{ColumbiaCancer }%
\author[1]{r/Science AMAs}%
\affil[1]{Affiliation not available}%


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  \date{June 13, 2024}


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\begin{abstract}
Hi Reddit, We're Paul Oberstein, MD and Manji Gulam, MD, PhD, from the
Medical Oncology department at Columbia University Medical Center. We
are so happy to be here and answer your questions! We work as part of a
multidisciplinary center, the Pancreas Center at Columbia University,
where we specialize in seeing patients with pancreatic cancer and other
gastrointestinal malignancies. Dr. Oberstein: Assistant Professor of
Medicine within the Division of Medical Oncology at Columbia University
Medical Center. My research focuses on developing novel clinical trials
for patients with pancreatic cancer. Research trials emphasize novel
agents and translation of promising concepts from the laboratory to the
clinic. In particular, I am focused on developing collaborations to
expand options for treatment as well as supportive care for patients
with advanced cancer. I am the Principal Investigator for over 10 active
trials including both therapeutic and supportive care studies, and am
conducting research studying the interplay between tumor associated
stroma and epithelial cells utilizing mouse models of pancreatic cancer
in the Herbert Irving Comprehensive Cancer Center. Pancreatic cancer:
why is it so hard to treat? Dr. Manji: Assistant Professor of Medicine
within the Division of Medical Oncology at the Columbia University
Medical Center. I conduct translational research with the overall goal
to develop new treatments for cancer. My focus is on gastrointestinal
malignancies, particularly pancreas adenocarcinoma, on which I am
conducting preclinical combination immunotherapy studies on genetically
engineered mice with pancreas cancer in the laboratory at the Herbert
Irving Comprehensive Cancer Center. I am currently the principal
investigator of multiple novel combination studies that include
immunotherapy in pancreas, esophageal, gastric, and liver cancers, and
currently developing other unique strategies to tackle these difficult
to treat diseases. I am the recipient of the Young Investigator Award
for his preclinical studies in Pancreas Cancer by the American Society
of Clinical Oncology. Immune Targeting in Gastrointestinal Malignancies:
Finding the Right Combination for the Right Site Dr Oberstein signing
as: PO Dr Gulam signing as: MG Edit: Hi Reddit! We're here, let's get to
it. Proof Edit 2: Thanks for all your great questions, Reddit. We're
signing off for now, but we'll be checking in tonight and tom morning so
keep the questions coming.%
\end{abstract}%



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