Overview Within the communication process, numerous barriers exist that may disrupt or even eliminate interpersonal interaction. Given the large number of potential barriers that exist in pharmacy practice settings, it is a wonder that any commu- nication takes place at all. Some barriers are rather obvious, while others are more subtle. The key is to identify when barriers exist and then develop strate- gies that minimize them. This chapter provides an overview of general barrier issues within communication and provides examples in a few key areas (practice environment, personal issues, administrative priorities, and lack of time and resources). Additional types of barriers will be discussed in subsequent chapters as they relate to the more specific aspects of the communication process.