METHODS
A retrospective case review was performed with identification of all patients from a single tertiary care center providing service throughout the Midwest region. Patients were identified from electronic medical records from January 2003 to July 2021 with the diagnostic codes for systemic juvenile idiopathic arthritis and with diagnostic codes for interstitial lung disease, dyspnea, or hypoxemia at any time throughout their lifetime. A total of 134 patients were identified to have both a diagnosis of sJIA and at least one of the above respiratory complaints; 9 were confirmed on manual chart review to have true interstitial lung disease related to sJIA. Of these 9 patients, they had to meet both the International League of Associations for Rheumatology (ILAR) criteria for sJIA from two different pediatric rheumatology reviewers and meet criteria for ChILD from two different pediatric pulmonology reviewers11. Race/ethnicity data were obtained via review of medical records and were categorized by self-identified ethnicity as well as self-identification with Hispanic/Latino or Non-Hispanic/Latino origin. The case series was reviewed by the Children’s Mercy Institutional Review Board and an exemption was granted.