Results
A total of 163 hospitalized elderly patients were included in this
study, including 84 patients in the COVID-19 group and 79 in the CNT
group. The age of the patients in the two groups was tested by
Kolmogorov-Sminov test, with the results of COVID-19 group Z =
0.086, P = 0.162 and CNT group Z = 0.162,P < 0.001. The data showed a non-normal distribution,
and statistical analysis was performed by Mann-Whitney U test
(non-parametric test). Chi-square test was used to compare the gender
between the two groups. The test results of age and gender were shown in
Table 1, and there was no statistically significant difference
(P > 0.05).
Among 163 hospitalized elderly patients with sputum samples, 195 strains
of bacteria were isolated, including 22 Gram-positive bacteria (11.3%)
and 178 Gram-negative bacteria (88.7%). The top 10 pathogenic bacteria
were Klebsiella pneumonia , Pseudomonas
aeruginosa ,Acinetobacter baumannii, Stenotrophomonas
maltophilia ,Escherichia coli ,Staphylococcus aureus ,Streptococcus pneumoniae ,Haemophilus
influenza ,Enterobacter cloacae , and Enterobacter
aerogenes. accounting for 30.3%, 19.0%, 12.8%, 7.7%, 7.2%, 6.7%,
4.6%, 3.1%, 2.1%, and 1.5%, respectively, and the remaining bacteria
accounted for 6.0%. See Table 2 and Figure 1.
Single bacteria infection occurred in 163 cases (82.2%, 134/163) of
hospitalized elderly patients, and mixed infection with two bacteria
occurred in 25 cases (16.0%, 26/163), and mixed infection with three
bacteria occurred in 3 cases (1.8%, 3/163).
The distribution of bacteria in COVID-19 group (98 strains) and CNT
group (97 strains) was analyzed. Except for Acinetobacter
baumannii and Stenotrophomonas maltophilia , there was no
statistical difference in the distribution of other strains. The
composition ratio of Acinetobacter baumannii in the COVID-19
group (7.1%) was lower than that in the CNT group (18.6%), the
difference was statistically significant (P = 0.017); the
composition ratio of Stenotrophomonas maltophilia in the COVID-19
group (12.2%) was higher than that in the CNT group (3.1%), the
difference was statistically significant (P = 0.016). See Table