<div>CRP= C reactive protein; WBC = White Blood Cells; RBC = Red Blood Cells;
HGB = Hemoglobin; PLT = Platelets; %Neu = Neutrophils (percentage);
%Lymph = Lymphocytes (percentage); %Mon = Monocytes (percentage);
%Eos = Eosinophils (percentage); #Eos = Eosinophils (number); %Bas =
Basophils (percentage); #Bas = Basophils (number);#Neu = Neutrophils
(number); #Lymph = Lymphocytes (number); #Mon = Monocytes (number);
HCT = Hematocrit; MCV = Mean Corpuscular Volume; MCHC = Mean Corpuscular
Hemoglobin Concentration; MCH = Mean Corpuscular Hemoglobin; RDW-SD =
Red Cell Distribution Width-Standard Deviation; RDW-CV = Red Cell
Distribution Width-Coefficient of Variation; PDW = Platelet Distribution
Width; MPV = Mean Platelet Volume; PCT = Plateletcrit; P-LCR = Platelet
Large Cell Ratio.</div><div><b>Predictor variable screening results</b></div><div><div>Among the baseline indicators in the training cohort, univariate
logistic regression showed age,
White Blood Cells (WBC), Red Blood Cells (RBC), Neutrophils percentage
(%Neu), Neutrophils number (#Neu), Lymphocytes percentage (%Lymph),
Monocytes percentage (%Mon), Red Cell Distribution Width-Standard
Deviation (RDW-SD), Platelet Distribution Width (PDW), Mean Platelet
Volume (MPV), Platelet Large Cell Ratio (P-LCR),
CRP natural log-transformed value
(InCRP), Eosinophils (percentage) (%Eos), Basophils percentage (%Bas),
Basophils number (#Bas) as possible predictors(<i>p &lt;
0.1</i>), further multivariate logistic regression showed
age,
CRP natural log-transformed value (InCRP), Neutrophils percentage
(%Neu), and Monocytes percentage (%Mon) as independent predictors
(<i>p &lt; 0.05</i>)( TABLE 2).
Three predictors with non-zero
coefficients were obtained by Lasso regression (screening lambda by
10-fold cross-validation, based on lambda.1se, i.e., the maximum lambda
corresponding to an error mean within one standard deviation of the
minimum): age, CRP natural log-transformed value (InCRP), Monocytes
percentage (%Mon) (FIGURE 2). To reduce irrelevant and redundant
information, the variables
selected by both screening methods were taken as the final selected
predictor variables:
age, natural log-transformed
value (InCRP), and Monocytes percentage (%Mon).</div></div>